Built next to the Church of San Michele Arcangelo, it is attached to the Convent of St. Anthony of Padua, which tradition says was visited by the saint during his journey to Sicily between 1222 and 1223.
Both buildings were damaged by the earthquake of 1693 and the Franciscans rebuilt the convent on the same site.
As for the church, it was decided to rebuild and enlarge the one originally dedicated to St. Catherine, which had been abandoned, and to name it after the Annunciation.
The Baroque niche dedicated to St. Anthony comes from the remains of the old church. The interior, with a single nave, is decorated with valuable frescoes depicting characters from the Old and New Testaments.
Other notable works are the 18h-century oil paintings depicting the Annunciation and St. Francis of Assisi.
On the marble high altar are the statues of St. Lucia, the Immaculate Virgin and St. Anthony of Padua.